Intracytoplasmic Hemozoin (Malarial Pigment) in a Case of Severe, Aparasitemic Plasmodium falciparum Malaria
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منابع مشابه
Intracytoplasmic Hemozoin (Malarial Pigment) in a Case of Severe, Aparasitemic Plasmodium falciparum Malaria
A 17-year-old girl from Togo with a β-thalassemia maior was seen at an emergency department with high fever, coma, and severe anemia (Hb < 3 g/dL ). No malaria parasites were found on thin film and thick smears in the first few days of the infection. Despite the failure to observe Plasmodium intraerythrocytic forms in the bloodstream, many white blood cells showed brown, birefringent, intracyto...
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which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. A 33-year-old man presented with left hypochondrium pain and high-grade fever for 1 week and generalized convulsions followed by persistent unconsciousness. 2.8 mg/dL. His coagulation profile showed an international normalized ratio of 2.4, along with severe...
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Malaria is the world’s leading parasitic disease and affects approximately 40% of the world’s population (approximately 2.4 billion people) in more than 100 countries.(1) The disease, that is caused for Plamodium spp., particularly affects populations in tropical and subtropical areas, especially in developing and underdeveloped countries. Brazil has the largest number of cases on the American ...
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Background: Falciparum malaria is a severe health burden worldwide. Antigen presenting cells are reported to be affected by erythrocytic stage of the parasite. Malarial hemozoin (HZ), a metabolite of malaria parasite, has adjuvant properties and may play a role in the induction of immune response against the parasite. Objective: To determine the immunological impact of hemozoin on the capacity ...
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ژورنال
عنوان ژورنال: The American Journal of Tropical Medicine and Hygiene
سال: 2011
ISSN: 0002-9637,1476-1645
DOI: 10.4269/ajtmh.2011.10-0687